By default, endpoint clients synchronize with the portal approximately every four hours. If an immediate sync is needed on a particular client, you can achieve this by opening Admin By Request from the tray tool (Windows) or menu bar (macOS and Linux) and selecting About Admin By Request.
At the same time, you should verify that connectivity is OK by clicking the Connectivity button.
Refer to Synchronizing Clients with the Portal for more information, or if you are having problems with synchronization.